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However, no research have been performed on the affiliation between PD and the BDNF gene via evaluation of the associated haplotypes. Shimizu E, Hashimoto K, Koizumi H, Kobayashi K, Itoh K, Mitsumori M, et al. No affiliation of the brain-derived neurotrophic issue gene polymorphisms with panic dysfunction. Three previous research have been printed on the associations between PD and the 196G/A and, 270C/T SNPs of the BDNF gene,16,17,18 although they detected no vital associations. In this research, we not solely investigated the differences in genotype and allele frequencies between PD patients and controls, but additionally recognized the genetic sequence affiliation with PD through haplotype analysis. The identification of positive associations will assist to determine the pathogenesis of PD.

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